Chronic bowel disorders



Chronic bowel disorders Overview Individual symptoms of chronic bowel disorders need specific treatment including dietary manipulation as well as drug treatment and the maintenance of a liberal fluid intake. 

Clostridium difficile infection :

Clostridium difficile infection is caused by colonisation of the colon with Clostridium difficile and production of toxin. It often follows antibiotic therapy and is usually of acute onset, but may become chronic. It is a particular hazard of ampicillin , amoxicillin , co-amoxiclav , second- and third-generation cephalosporins, clindamycin , and quinolones, but few antibacterials are free of this side-effect. Oral metronidazole  or oral vancomycin  are used as specific treatment; vancomycin may be preferred for very sick patients. Metronidazole can be given by intravenous infusion if oral treatment is inappropriate.
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