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| Example of A Medicine containing Simethicone |
in this Page:
The scientific name
chemical composition
Mode of Action
Medical Uses
Availability and examples of trade names in the world
Use in pregnancy and lactation:
The side effects
This drug Interacts with
Contraindications
use for babies
Legal status
Route of administration
Excretion
Bioavailability
Chemical formula
Use of medication
Metabolism
Doses and methods of Adminstration
Duration of Action
Storage
Missed dose:
Stopping the medication:
overdose:
Elderly:
Driving and use machines:
Simethicone
Systematic (IUPAC) name
Poly(dimethylsiloxane), silicon dioxide
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The chemical composition of the active ingredient of the drug
Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel.
Mechanism Of Action
Simethicone is a substance that reduces The surface tension of gas bubbles inside the stomach, makes it easier to disapper through collecting in large bubbles out of the body easily by gases out of
The body, and does not reduces its formation (which is mostly formed by air swallowing or because of Some types of food ) but makes easy exit for it , and thus reduces flatulence, or bloating in the abdomen and bowel pain and discomfort caused /.
Medical uses
SAFETY
Simethicone is not absorbed into the bloodstream and is
therefore considered relatively safe. National Institutes of
Health (NIH) reports there are usually no side effects when
simethicone is taken as directed. Although simethicone has
also been promoted as a treatment for colic in babies,
randomised controlled trials have not demonstrated efficacy
for this use despite traditional views on the subject, colic
does not appear to be caused by gas
Also is used to clean the colon of gas before a radiograph (Rntjn) of the colon.
Availability and examples of trade names in the world
Available in pharmacies in the form of oral capsules, and chewable tablets and oral drops given to infants.
Capsules: 125 mg 166 mg 180 mg
ORAL DISINTEGRATING STRIP
40 mg 62.5 mgOral Drop: 40 mg / 0.6 ml
Chewable tablets: 80 mg 125 mg
Simethicone is generally available over the counter under many brand names in varying dosage sizes and combinations with other drugs, including: ·
1 Air-x
2 Anaflat
3 Antacil
4 Antiflat
5 Baby's Own Infant Drops
6 Bearse
7 Bloateze
8 Bloateze
9 Bobotik
10 De-gas
11 Deflatine
12 Di-gel
13 Disflatyl
14 Dulcogas
15 Espumisan
16 Factor Ag 200
17 Flatin
18 Flatulex
19 Gas X
20 Gas-med
21 Gasaid
22 Gascon
23 Gaszym
24 Gazim X
25 Genasyme
26 Imodium Multi-symptom Relief
27 Imogas
28 Imonogas
29 Infacol
30 Infacon
31 Kremil-s
32 Kupla Stop (finland) ·
33 Lefax (germany) ·
34 Little Tummys ·
35 Luftal (brazil and Mexico) ·
36 Maalox Anti-gas ·
37 Maalox Max ·
38 Mag77
39 Meteoxane (france) ·
40 Metsil (turkey) ·
41 Minicol (pakistan)
42 Minifom (norway, Sweden)
43 My Baby Gas Relief Drops
44 Mylanta Gas Relief ·
45 Mylanta Gas ·
46 Mylicon Drops ·
47 Mylicongas (italy) ·
48 Ovol ·
49 Phazyme ·
50 Rantac-mps (unique Pharma, India) ·
51 Refalgin (it) ·
52 Rennie Deflatine ·
53 Rolaids ·
54 Sab Simplex ·
55 Silan (uruguay) ·
56 Siloxogene (india) ·
57 Simeco (philippines) ·
58 Simicol (israel) ·
59 Telament Colic Drops (south Africa) ·
60 Triaerom (peru) ·
61 Vitane Colicez Oral Drops 30 Ml
62 Windeze (uk)
63 Infacol
64 Baby Rest
65 Gaseoflatex
66 Disflatyl
67 Deflat
68 Dentinox
69 Salinal tablets and oral drops
70 Softgels Anti-
71Simethicone drops Amiriya
72 phazyme tablets
73 Flatidyl
74 Flaticol
75 Flaticon
76 colic ez
Use in pregnancy and lactation:
Pregnancy category "C": there are currently no adequate studies to confirm the safety of
The use of therapy to the fetus; therapy is used if the therapeutic benefit
Outweigh the risk to the fetus. You should consult your doctor or pharmacist before taking medication
Breast feeding:
Permissible. There are no signs of a danger to the child.
The side effects
Simethicone is not absorbed in the body does not enter the bloodstream, so it is considered relatively safe.
Britain's National Institute of Health reported that usually there are no side effects when taken according to the instructions
More rare side effects that occur sometimes Such as mild diarrhea, nausea, regurgitation, vomiting
Hiccups (Hiccup), and the increased release of gas .
This drug does not interfere with any other drugs
But thyroid drugs such as thyroxine may reduce absorption
Make least 4 hours gap when using them together.
Contraindications
Only in patients who have demonstrated hypersensitivity to simethicone (watch out for the symptoms of hypersensitivity) or any other component of the drug components.
Safety in Children
Safe for use in infants from the first day of birth, and can be used because it does not get absorbed in blood but works locally in the intestine.
The legal status (United States)
over-the-counter drug
Route of administration
Oral (by mouth)
Excretion
through feces
Bioavailability
is not absorbed through the intestines
Metabolism
Not Metabolized
Chemical formula
How to use
Taken after meals and at bedtime.
-Chewable tablets: chew the tablet well and not swallow whole Tablet. - Oral Strip: Stripis placed on the tongue and left to dissolve.
- Liquid form:
- Must Shake well before use
- It can be mixed with water
Doses and methods of use
The usual dose for adults for flatulence and gases:
40-125 mg orally after meals and at bedtime, so that the daily dose does not exceed 500 mg / 24 hours.
The usual dose for adults for Functional gastrointestinal disorder:
40-125 mg orally after meals and at bedtime, so that the daily dose does not exceed 500 mg / 24 hours.
The usual dose for children:
from birth to less than 2 years: 20 mg oral 4 times a day.
2-12 years: 40 mg oral 4 times a day.
12-18 years: 40-125 mg orally after meals and at bedtime, so that the daily dose does not exceed 500 mg / 24 hours.
Starting the effect:
After 15-30 minutes of taking the drug.
Duration of action
4-6 hours.
Storage :
You must save the medication in a container sealed in a cool, dry place, away from the reach of children.
Missed dose:
Take the next scheduled dose as usual.
Stopping the medication:
You can stop taking the medication if you don't feel you need it.
overdose:
Eating Accidental overdose is not cause for concern. But if you notice any particular symptoms or if the overdose was very big, you should inform your doctor.
Elderly:
There are no particular problems.
Driving and use machines:
There are no known problems.
Linkage
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The term in Arabic: Smetkon.
The term in English: Simethicone.
Classification of medicine: Anti flatulence
Antiflatulent. Category :.
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